Non-viable LAD infarct; A 67-year gentleman presents with triple-vessel disease. Echocardiography at outside facility revealed enlarged left ventricle with LVEF 45% and regional wall motion abnormality; 45 year old gentleman presented with worsening heart failure. No prior investigations were done.


Undersöker vi bara anterior STEMI (dvs LAD) förefaller betablockad att minska infarktstorlek och förbättra VKEF. Ju snabbare behandling ges 

Subsequently, these patients are more likely to undergo PCI more than 24 hours from onset of symptoms compared to patients with more readily recognizable left anterior descending (LAD) and right coronary artery (RCA) occlusions. 5 LCX lesions are associated with increased risk of heart failure and mortality at 90 days and 1 year compared to RCA and LAD lesions. 7 In addition, there have been Several ECG criteria have been reported to indicate a LAD artery occlusion proximal to the first septal perforator branch: (1) ST elevation in lead aVR (2) right bundle branch block (3) ST depression in lead V5 and (4) ST elevation in lead V1 >2.5mm Birnbaum et al found no association between ST elevation in lead V1 and LAD artery occlusion proximal to the first septal branch in one series LAD Occlusion Infarct Ischaemia-reperfusion LAD Occlusion Infarct AAR AB Permanent ligation Fig. 1. Comparison of the infarcts generated after permanent ligation and ischaemia-reperfusion techniques. (A) Permanent occlusion of the left anterior descending coronary artery (LAD) as a model of myocardial infarction (MI) leads to a large, permanent A major challenge in developing new treatments for myocardial infarction (MI) is an improved understanding of the pathophysiology of hypoxic tissue damage and the activation of endogenous adaptive programs to hypoxia.

Lad infarct

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Ook zien we in V2en V3flinke ST-depressies hetgeen wijst op een mogelijke infarcering van de achterwand(posterior). Se hela listan på Then he went into the room; the lad, by his own directions, following him in; and the door being left wide open. View in context Very precious to Jo was the friendship of the lads , their penitent sniffs and whispers after wrongdoing, their droll or touching little confidences, their pleasant enthusiasms, hopes, and plans, even their misfortunes, for they only endeared them to her all the more. The LAD-perfused area, both in the RV and LV, was defined as the percentage of the myocardial volume showing thioflavin-S staining. Infarct size was designated as the percentage of the myocardial volume that failed to stain with 2,3,5-triphenyltetrazolium chloride.

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av RCM de Jong · 2018 · Citerat av 20 — Acute myocardial infarction (MI) initiates a massive inflammatory in the 4th intercostal space and the left anterior descending (LAD) coronary 

LAD was infarct-related in 53 (65.4%) patients, circumflex (CxA) involved in 28 (34.6%) cases. Distal LMCA lesion was in 45 patients (55.6%).

Lad infarct

Vagal nerve stimulation reduces infarct size via a mechanism involving the alpha-7 nicotinic acetylcholine receptor and down-regulation of cardiac and vascular 


Lad infarct

Due to the relevance of oxygen in metabolism, molecular adaptation to hypoxia driven by the hypoxia-inducible factors (HIFs) and the HIF-regulating prolyl hydroxylase … 2014-04-05 The p38 mitogen-activated protein kinases (p38s) are Ser/Thr kinases that are activated as a result of cellular stresses and various pathological conditions, including myocardial ischemia/reperfusion. p38 activation has been shown to accentuate myocardial injury and impair cardiac function. Inhibition of p38 activation and its activity has been proposed to be cardioprotective by slowing the The left anterior descending artery (also LAD, anterior interventricular branch of left coronary artery, or anterior descending branch) is a branch of the left coronary artery.
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Coronary angiogram showed 90% stenosis in mid-LAD, distal to the previous stent and proximal to an anomalously originating RCA from mid-LAD.

The LAD itself continues distally and may wrap around the tip of the LV to supply the apex. An example of an acute LAD infarct on echocardiography is shown in Video 18.10.
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Quixote/M Quixotism/M Quonset R/MG RAF RAM/S RBI/S RC RCA RCS RD RDA infarct/SM infarction/MS infatuate/XNGSD infatuation/M infect/AGEUDVRS 

Anterior myocardial infarction carries the poorest prognosis of all infarct locations, due to the larger area of myocardium infarct size. LAD (left anterior descending artery) LAD försörjer följande myokardområden: Septums främre två tredjedelar (anteroseptalt).


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Anterolateraal infarct door occlusie van de LAD. Doorsnede van een acuut voorwandinfarct. Een voorbeeld van een anterolateraal infarct. ECG-kenmerken: Proximal LAD occlusions may cause ST-elevations not only in the anterior, septal and lateral precordial leads but also in the high lateral limb leads (I and aVL). When concomitant ST-segment elevation is present in leads I or aVL, it usually signifies occlusion of the LAD before the first diagonal branch (D1) (see Figures 3.2 and 3.3).